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1

Insect Conservation

Pyle, R, Bentzien, M, Opler, P

Journal:

Annual Review of Entomology

Year:

1981

Language:

english

File:

PDF, 726 KB

english, 1981

2

Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design

Brian N. Cook, Jörg Bentzien, Andre White, Peter A. Nemoto, Ji Wang, Chuk C. Man, Fariba Soleymanzadeh, Hnin Hnin Khine, Mohammed A. Kashem, Stanley Z. Kugler Jr., John P. Wolak, Gregory P. Roth, Stép

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 417 KB

english, 2009

3

Cabozantinib (XL184), a Novel MET and VEGFR2 Inhibitor, Simultaneously Suppresses Metastasis, Angiogenesis, and Tumor Growth

Yakes, F. M., Chen, J., Tan, J., Yamaguchi, K., Shi, Y., Yu, P., Qian, F., Chu, F., Bentzien, F., Cancilla, B.

Journal:

Molecular Cancer Therapeutics

Year:

2011

Language:

english

File:

PDF, 1.99 MB

english, 2011

4

Identification of a Potent Sodium Hydrogen Exchanger Isoform 1 (NHE1) Inhibitor with a Suitable Profile for Chronic Dosing and Demonstrated Cardioprotective Effects in a Preclinical Model of Myocardial Infarction in the Rat

Huber, John D., Bentzien, Jörg, Boyer, Stephen J., Burke, Jennifer, De Lombaert, Stéphane, Eickmeier, Christian, Guo, Xin, Haist, James V., Hickey, Eugene R., Kaplita, Paul, Karmazyn, Morris, Kemper,

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 765 KB

english, 2012

5

Relapsing nasal glioma in a three-week-old infant

Schroth, Michael, Wolf, Stephan, Bentzien, Sabine C., Wagner, Maren, Rupprecht, Thomas

Journal:

Medical and Pediatric Oncology

Year:

2000

Language:

english

File:

PDF, 108 KB

english, 2000

6

Effective way of modeling chemical catalysis: Empirical valence bond picture of role of solvent and catalyst in alkylation reactions

Vill�, Jordi, Bentzien, J�rg, Gonz�lez-Lafont, �ngels, Lluch, Jos� M., Bertran, Juan, Warshel, Arieh

Journal:

Journal of Computational Chemistry

Year:

2000

Language:

english

File:

PDF, 429 KB

english, 2000

7

Separating NP-Completeness Notions under Strong Hypotheses

Klaus Ambos-Spies, Levke Bentzien

Journal:

Journal of Computer and System Sciences

Year:

2000

Language:

english

File:

PDF, 227 KB

english, 2000

8

Trifluoromethyl group as a pharmacophore: Effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand

Raj Betageri, Yan Zhang, Renee M. Zindell, Daniel Kuzmich, Thomas M. Kirrane, Jörg Bentzien, Mario Cardozo, Alison J. Capolino, Tazmeen N. Fadra, Richard M. Nelson, Zofia Paw, Daw-Tsun Shih, Cheng-Kon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 418 KB

english, 2005

9

2-Aminobenzimidazoles as potent ITK antagonists: trans-stilbene-like moieties targeting the kinase specificity pocket

Ho Yin Lo, Jörg Bentzien, Roman W. Fleck, Steven S. Pullen, Hnin Hnin Khine, Joseph R. Woska Jr., Stanley Z. Kugler, Mohammed A. Kashem, Hidenori Takahashi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 202 KB

english, 2008

10

5-Aminomethylbenzimidazoles as potent ITK antagonists

Doris Riether, Renée Zindell, Jennifer A. Kowalski, Brian N. Cook, Jörg Bentzien, Stéphane De Lombaert, David Thomson, Stanley Z. Kugler Jr., Donna Skow, Leslie S. Martin, Ernest L. Raymond, Hnin Hnin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 527 KB

english, 2009

11

2-Aminobenzimidazoles as potent ITK antagonists: de novo design of a pyrrole system targeting additional hydrogen bonding interaction

Ho Yin Lo, Jörg Bentzien, Andre White, Chuk C. Man, Roman W. Fleck, Steven S. Pullen, Hnin Hnin Khine, Josephine King, Joseph R. Woska Jr., John P. Wolak, Mohammed A. Kashem, Gregory P. Roth, Hidenori

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 252 KB

english, 2008

12

Maschinelle Autotransfusionsverfahren Anwendung und Einfluss auf Zytokine und Leukozyten im autologen gewaschenen Erythrozytenkonzentrat

F. Bentzien, J.M. Brand, E. Röhrs, H. Munkel, P. Schmucker

Journal:

Der Anaesthesist

Year:

2000

Language:

german

File:

PDF, 384 KB

german, 2000

13

DemQSAR: predicting human volume of distribution and clearance of drugs

Ozgur Demir-Kavuk, Jörg Bentzien, Ingo Muegge, Ernst-Walter Knapp

Journal:

Journal of Computer-Aided Molecular Design

Year:

2011

Language:

english

File:

PDF, 660 KB

english, 2011

14

Autologous blood donor screening indicated a lower prevalence of viral hepatitis in East vs West Germany: epidemiological benefit from established health resources

J. Wiegand, B. Luz, A.-K. Mengelkamp, R. Moog, J. Koscielny, I. Halm-Heinrich, C. Susemihl, F. Bentzien, J. Diekmann, D. Wernet, R. Karger, K. Angert, A. Schmitt-Thomssen, V. Kiefel, K. Lutter, R. Hes

Journal:

Journal of Viral Hepatitis

Year:

2009

Language:

english

File:

PDF, 135 KB

english, 2009

15

Intraoperative Electromyography for Identification of the Trapezius Muscle Innervation: Clinical Proof of a New Anatomical Concept

Antonius C. Kierner, M. Burian, S. Bentzien, W. Gstoettner

Journal:

The Laryngoscope

Year:

2002

Language:

english

File:

PDF, 560 KB

english, 2002

16

Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores

Raj Betageri, Thomas Gilmore, Daniel Kuzmich, Thomas M. Kirrane, Jörg Bentzien, Dieter Wiedenmayer, Younes Bekkali, John Regan, Angela Berry, Bachir Latli, Alison J. Kukulka, Tazmeen N. Fadra, Richard

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 933 KB

english, 2011

17

The design, synthesis, and biological evaluation of potent receptor tyrosine kinase inhibitors

Moon H. Kim, Amy Lew Tsuhako, Erick W. Co, Dana T. Aftab, Frauke Bentzien, Jason Chen, Wei Cheng, Stefan Engst, Levina Goon, Rhett R. Klein, Donna T. Le, Morrison Mac, Jason J. Parks, Fawn Qian, Monic

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 999 KB

english, 2012

18

Discovery of a Novel Class of Potent and Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists

Ibrahim, Mohamed A., Johnson, Henry W. B., Jeong, Joon Won, Lewis, Gary L., Shi, Xian, Noguchi, Robin T., Williams, Matthew, Leahy, James W., Nuss, John M., Woolfrey, John, Banica, Monica, Bentzien, F

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 108 KB

english, 2012

19

89 POSTER Evaluation of peripheral blood cells and hair as surrogate tissues for clinical trial pharmacodynamic assessment of XL147 and XL765, inhibitors of the PI3K signaling pathway

A.D. Laird, A. Sillman, B. Sun, A. Mengistab, F. Chu, M. Lee, B. Cancilla, S.K. Aggarwal, F. Bentzien

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

20

Crowd computing: using competitive dynamics to develop and refine highly predictive models

Bentzien, Jörg, Muegge, Ingo, Hamner, Ben, Thompson, David C.

Journal:

Drug Discovery Today

Year:

2013

Language:

english

File:

PDF, 350 KB

english, 2013

21

Toll like receptor 2 agonists lipoteichoic acid and peptidoglycan are able to enhance antigen specific IFNγ release in whole blood during recall antigen responses

Dammermann, Werner, Wollenberg, Lisa, Bentzien, Frank, Lohse, Ansgar, Lüth, Stefan

Journal:

Journal of Immunological Methods

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

22

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation

Gieseke, Friederike, Kruchen, Anne, Tzaribachev, Nikolay, Bentzien, Frank, Dominici, Massimo, Müller, Ingo

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 654 KB

english, 2013

23

Function-regulating pharmacophores in a sulfonamide class of glucocorticoid receptor agonists

Kuzmich, Daniel, Bentzien, Jörg, Betageri, Raj, DiSalvo, Darren, Fadra-Khan, Tazmeen, Harcken, Christian, Kukulka, Alison, Nabozny, Gerald, Nelson, Richard, Pack, Edward, Souza, Donald, Thomson, David

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 913 KB

english, 2013

24

Discovery of a potent and dissociated non-steroidal glucocorticoid receptor agonist containing an alkyl carbinol pharmacophore

Razavi, Hossein, Riether, Doris, Harcken, Christian, Bentzien, Jörg, Dinallo, Roger M., Souza, Donald, Nelson, Richard M., Kukulka, Alison, Fadra-Khan, Tazmeen N., Pack, Edward J., Zuvela-Jelaska, Lji

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.08 MB

english, 2014

25

Substituted phenyl as a steroid A-ring mimetic: Providing agonist activity to a class of arylsulfonamide nonsteroidal glucocorticoid ligands

DiSalvo, Darren, Kuzmich, Daniel, Bentzien, Jörg, Regan, John, Kukulka, Alison, Fadra-Khan, Tazmeen, Nelson, Richard, Harcken, Christian, Thomson, David, Nabozny, Gerald

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

26

Opposing Actions of Intact and N-Terminal Fragments of the Human Prolactin/Growth Hormone Family Members on Angiogenesis: An Efficient Mechanism for the Regulation of Angiogenesis

Ingrid Struman, Frauke Bentzien, Hsinyu Lee, Veronique Mainfroid, Gisela D'Angelo, Vincent Goffin, Richard I. Weiner and Joseph A. Martial

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.85 MB

english, 1999

27

Lettre aux conseils-généraux de France en 1860: précédée d'une pétition a l'empereur et suivie d'un extrait du journal de la société de la morale chrétienne relatif a un projet de rédaction d'un code pénal-modèle applicable a l'Europe entière

Bentzien, J. D.

File:

PDF, 1.82 MB

28

Nonsteroidal Dissociated Glucocorticoid Agonists Containing Azaindoles as Steroid A-Ring Mimetics

Riether, Doris, Harcken, Christian, Razavi, Hossein, Kuzmich, Daniel, Gilmore, Thomas, Bentzien, Jörg, Pack, Edward J., Souza, Donald, Nelson, Richard M., Kukulka, Alison, Fadra, Tazmeen N., Zuvela-J

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.47 MB

english, 2010

29

Hybrid ab Initio Quantum Mechanics/Molecular Mechanics Calculations of Free Energy Surfaces for Enzymatic Reactions: The Nucleophilic Attack in Subtilisin

Bentzien, J., Muller, R. P., Florián, J., Warshel, A.

Journal:

Journal of Physical Chemistry B

Year:

1998

Language:

english

File:

PDF, 187 KB

english, 1998

30

An in Silico Method for Predicting Ames Activities of Primary Aromatic Amines by Calculating the Stabilities of Nitrenium Ions

Bentzien, Jörg, Hickey, Eugene R., Kemper, Raymond A., Brewer, Mark L., Dyekjær, Jane D., East, Stephen P., Whittaker, Mark

Journal:

Journal of Chemical Information and Modeling

Year:

2010

Language:

english

File:

PDF, 16.68 MB

english, 2010

31

Quinol-4-ones as Steroid A-Ring Mimetics in Nonsteroidal Dissociated Glucocorticoid Agonists

Regan, John, Lee, Thomas W., Zindell, Renée M., Bekkali, Younes, Bentzien, Jörg, Gilmore, Thomas, Hammach, Abdelhakim, Kirrane, Thomas M., Kukulka, Alison J., Kuzmich, Daniel, Nelson, Richard M., Prou

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 150 KB

english, 2006

32

Theoretical Investigations on the Regio- and Stereochemistry of the Photochemical [2 + 2] Cycloaddition of Propene

Bentzien, Joerg, Klessinger, Martin

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 830 KB

english, 1994

33

[IEEE Comput. Soc Computational Complexity. Twelfth Annual IEEE Conference - Ulm, Germany (24-27 June 1997)] Proceedings of Computational Complexity. Twelfth Annual IEEE Conference - Separating NP-completeness notions under strong hypotheses

Ambos-Spies, K., Bentzien, L.

Year:

1997

Language:

english

File:

PDF, 684 KB

english, 1997

34

In Vitro and In Vivo Activity of Cabozantinib (XL184), an Inhibitor of RET, MET, and VEGFR2, in a Model of Medullary Thyroid Cancer

Bentzien, Frauke, Zuzow, Marcus, Heald, Nathan, Gibson, Anna, Shi, Yongchang, Goon, Leanne, Yu, Peiwen, Engst, Stefan, Zhang, Wentao, Huang, Donghui, Zhao, Lora, Vysotskaia, Valentina, Chu, Felix, Bau

Journal:

Year:

2013

Language:

english

File:

PDF, 401 KB

english, 2013

35

Decomposition and graphical portrayal of the quantile score

Bentzien, Sabrina, Friederichs, Petra

Journal:

Quarterly Journal of the Royal Meteorological Society

Year:

2014

Language:

english

File:

PDF, 724 KB

english, 2014

36

CMV specific cytokine release assay in whole blood is optimized by combining synthetic CMV peptides and toll like receptor agonists

Dammermann, Werner, Bochmann, David, Bentzien, Frank, Komorowski, Lars, Steinhagen, Katja, Ullrich, Sebastian, van Lunzen, Jan, Lüth, Stefan

Journal:

Journal of Immunological Methods

Year:

2014

Language:

english

File:

PDF, 907 KB

english, 2014

37

Efficacy, safety, pharmacokinetics and pharmacodynamics of SAR245409 (voxtalisib, XL765), an orally administered phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor: a phase 1 expansion cohort in patients with relapsed or refractory lymphoma

Papadopoulos, Kyriakos P., Egile, Coumaran, Ruiz-Soto, Rodrigo, Jiang, Jason, Shi, Weiliang, Bentzien, Frauke, Rasco, Drew, Abrisqueta, Pau, Vose, Julie M., Tabernero, Josep

Journal:

Leukemia and Lymphoma

Year:

2015

Language:

english

File:

PDF, 5.40 MB

english, 2015

38

Crowdsourcing in pharma: a strategic framework

Bentzien, Jörg, Bharadwaj, Ragu, Thompson, David C.

Journal:

Drug Discovery Today

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

39

Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: An efficient mechanism for the regulation of angiogenesis

Struman, I., Bentzien, F., Lee, H., Mainfroid, V., D'Angelo, G., Goffin, V., Weiner, R. I., Martial, J. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 333 KB

english, 1999

40

Molecular Targeting of Antiangiogenic Factor 16K hPRL Inhibits Oxygen-Induced Retinopathy in Mice

Pan, Hao, Nguyen, Ngoc-Quynh-Nhu, Yoshida, Hiroshi, Bentzien, Frauke, Shaw, Lynn C., Rentier-Delrue, Francoise, Martial, Joseph A., Weiner, Richard, Struman, Ingrid, Grant, Maria B.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2004

Language:

english

File:

PDF, 599 KB

english, 2004

41

Combining computational and experimental screening for rapid optimization of protein properties

Hayes, R. J., Bentzien, J., Ary, M. L., Hwang, M. Y., Jacinto, J. M., Vielmetter, J., Kundu, A., Dahiyat, B. I.

Journal:

Proceedings of the National Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 327 KB

english, 2002

42

Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases

Qian, F., Engst, S., Yamaguchi, K., Yu, P., Won, K.-A., Mock, L., Lou, T., Tan, J., Li, C., Tam, D., Lougheed, J., Yakes, F. M., Bentzien, F., Xu, W., Zaks, T., Wooster, R., Greshock, J., Joly, A. H.

Journal:

Cancer Research

Year:

2009

Language:

english

File:

PDF, 734 KB

english, 2009

43

Inhibition of the T790M Gatekeeper Mutant of the Epidermal Growth Factor Receptor by EXEL-7647

Gendreau, S. B., Ventura, R., Keast, P., Laird, A. D., Yakes, F. M., Zhang, W., Bentzien, F., Cancilla, B., Lutman, J., Chu, F., Jackman, L., Shi, Y., Yu, P., Wang, J., Aftab, D. T., Jaeger, C. T., Me

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 801 KB

english, 2007

44

Induction of an angiogenic phenotype in endometriotic stromal cell cultures by interleukin-1

Lebovic, D. I., Bentzien, F., Chao, V. A., Garrett, E. N., Meng, Y.G., Taylor, R. N.

Journal:

Molecular Human Reproduction

Year:

2000

Language:

english

File:

PDF, 323 KB

english, 2000

45

Multi-centric determination of reference ranges for automated blood counts 1

Nebe, Thomas, Bentzien, Frank, Bruegel, Mathias, Fiedler, Georg Martin, Gutensohn, Kai, Heimpel, Hermann, Krebs, Nicole, Ossendorf, Manfred, Werner, Peter-Schuff, Stamminger, Gudrun, Baum, Hannsjörg

Journal:

Laboratoriums Medizin

Year:

2011

Language:

english

File:

PDF, 5.68 MB

english, 2011

46

Überlegungen und Notizen im Anschluß an die Lektüre von Ernst Klein, Die historischen Pflüge der Hohenheimer Sammlung landwirtschaftlicher Geräte_ und Maschinen. Ein kritischer Katalog = Quellen und Forschungen zur Agrargeschichte, Bd. 16

Bentzien, Ulrich

Journal:

Jahrbuch für Wirtschaftsgeschichte / Economic History Yearbook

Year:

1968

Language:

german

File:

PDF, 1.92 MB

german, 1968

47

Multizentrische Ermittlung von Referenzbereichen für Parameter des maschinellen Blutbildes/Multicentric Determination of Reference Ranges for Automated Blood Counts

Nebe, Thomas, Bentzien, Frank, Bruegel, Mathias, Fiedler, Georg Martin, Gutensohn, Kai, Heimpel, Hermann, Krebs, Nicole, Ossendorf, Manfred, Schuff-Werner, Peter, Stamminger, Gudrun, Baum, Hannsjörg

Journal:

Laboratoriums Medizin

Year:

2011

Language:

german

File:

PDF, 5.68 MB

german, 2011

48

Landmaschinentechnik in Mecklenburg (1800 bis 1959)

BENTZIEN, ULRICH

Journal:

Jahrbuch für Wirtschaftsgeschichte / Economic History Yearbook

Year:

1965

Language:

german

File:

PDF, 990 KB

german, 1965

49

Generating and Calibrating Probabilistic Quantitative Precipitation Forecasts from the High-Resolution NWP Model COSMO-DE

Bentzien, Sabrina, Friederichs, Petra

Journal:

Weather and Forecasting

Year:

2012

Language:

english

File:

PDF, 2.44 MB

english, 2012

50

WAS LEHRT UNS COLUMELLA?

Bentzien, Ulrich

Journal:

Jahrbuch für Wirtschaftsgeschichte / Economic History Yearbook

Year:

1975

Language:

german

File:

PDF, 202 KB

german, 1975

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